Corn is a versatile ingredient that plays a significant role in the production of alcohol, particularly in the form of corn-based spirits. These include bourbon, a type of whiskey that must contain at least 51% corn in its mash bill. Corn's high sugar content makes it an excellent source for fermentation, contributing to the distinctive sweetness and smoothness found in these spirits. The use of corn in alcohol production dates back to early American settlers, who utilized the abundant crop to create spirits that have become staples in American culture.

In the context of cocktails, corn-based spirits like bourbon and moonshine (a type of unaged corn whiskey) offer a rich, sweet flavor profile that pairs well with a variety of mixers and ingredients. Classic cocktails such as the Old Fashioned and the Mint Julep highlight the unique qualities of bourbon, while moonshine is often featured in more rustic or creative concoctions. The natural sweetness and full-bodied nature of corn-based spirits make them a popular choice for both traditional and innovative cocktail recipes.